Isgouhi Kaloshian

Rev. 01/01/2020


Dr. Kaloshian received her B.Sc. degree in Agriculture (1982) and M.Sc. in Plant Protection (1984) from the American University of Beirut, Lebanon.  Her Ph.D. research in Plant Pathology at the University of California, Riverside, was entitled, “Genetics of resistance to Meloidogyne spp. in wheat,” which she completed in 1989.  Following receipt of her doctoral degree, she pursued research as a Postdoctoral Fellow at UC-Riverside and UC-Davis.  In 1996, she was appointed Assistant Professor and Assistant Nematologist in the Department of Nematology at UC-Riverside, where she currently holds the position of Associate Professor.

Host resistance is generally thought to be one of the best strategies for nematode control.  Dr. Kaloshian has had a strong interest in host resistance for many years and currently is chair of the Society of Nematologists Plant Resistance to Nematodes Committee.  She has carried out extensive research on host resistance to various nematodes and toward characterizing resistance genetically in several plant species.  Her expertise ranges from field and greenhouse research to molecular biology.  She was a major contributor in the efforts to clone the nematode resistance gene Mi and is a co-inventor on the U.S. Patent.  She is also aware of the limitations of host resistance and has worked to develop new sources of resistance against known virulent isolates of nematodes from California.   She has also contributed her expertise in molecular biology to problems of characterization and identification of parasitic nematodes. Dr. Kaloshian has participated in the nematology teaching program at UC-Riverside and has been involved in several extension programs in California.


Dr. Kaloshian has worked on host resistance to plant parasitic nematodes for much of her career.  Her current focus is on nematode resistance in tomato.  The tomato gene Mi is the first cloned plant resistance gene with dual specificity to two unrelated organisms, a nematode and an aphid.  Her research group is currently pursuing two approaches to identify plant genes that control disease resistance.  The first approach is to genetically dissect the Mi-mediated resistance pathway to both nematodes and aphids.  She is using mutational analysis to identify and characterize plant genes that control nematode and aphid recognition and the subsequent expression of resistance.  The second approach is to isolate nematode resistance genes with novel specificities.  Currently only one nematode resistance gene, Mi, is present in cultivated tomato.  The value of Mi has been compromised by the appearance at several locations in California and in other parts of the world, variants of nematode strains and species that can infect Mi-bearing tomato.  Mi is not effective at temperatures above 28 C. She has initiated a DNA marker analysis as a step towards genetic mapping and cloning of new sources of resistance genes in the wild tomato species, Solanum peruvianum.

Dr. Kaloshian was awarded the Society of Nematologists Syngenta Recognition Award for Excellence in 2004.

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